Warren was meticulous in writing in her diary on a daily basis. Typical topics include the weather, meals prepared and eaten, other daily activities, visitors and with whom she visited, reading material, health and illnesses, her emotional state, etc. Warren kept singing birds and frequently had cats as companions as well. Addison Warren, when he was alive, and later Loanda Warren frequently made "gems" for breakfast, or small muffins or cakes typically using graham flour, which was whole wheat flour rather than white flour.

The 1879-1880 diary includes daily mentions of Warren's husband, who had given her the diary as a Christmas present in 1878. She typically refers to him as "A." or "Dearie." That diary also includes daily mentions of outdoor temperatures, numbers of eggs from their chickens, and frequent mentions of working at the "shop" in Olathe. (Warren appears to have done cobbling amongst other work, in addition to his farming.)

The 1893-1895 diary is very similar in topical coverage, while also including occasional descriptions of dreams about her dead mother and husband. This notebook is written in two directions; Warren used the back sides of the pages to write her 1894-1895 diary entries in reverse to the 1893 entries, as well as being upside down. Some individuals who appear frequently in this diary include a "Vesta" and "Mr. and Mrs. K," as well as Mrs. [Bouquin]. Warren often uses initials rather than full names when writing about other people.